Scientists from the Institute of Cytology of the Russian Academy of Sciences and the Almazov National Medical Center have for the first time created a cell model to study a rare genetic disease - Singleton-Merten syndrome, characterized by dangerous calcium deposition in blood vessels and organs. The model was developed using induced pluripotent stem cells derived from the blood of a patient with early manifestations of the disease. This discovery will make it possible to study in detail the mechanisms of pathology and develop therapies to slow its development.
Specialists from the Institute of Cytology of the Russian Academy of Sciences (INTS RAS) and the Almazov National Medical Center have developed a unique cell model to study Singleton-Merten syndrome, a rare genetic pathology that causes dangerous calcium deposits in blood vessels and organs. This discovery will make it possible to approach the development of therapies for the disease, the press service of the Scientific Center of the Russian Academy of Sciences reports.
Scientists for the first time created induced pluripotent stem cells (iPSCs) from the blood of a patient with Singleton-Merten syndrome. These cells carry a mutation that leads to early calcification of blood vessels.
Earlier we wrote that in 12 regions of our country introduced AI analysis of CT to recognize dementia and stroke. In addition, with drowsiness it is recommended to check the level of vitamin D and ferritin.