A new method of glioma treatment has been developed in Russia. Scientists suggest infecting the tumor with a virus for a subsequent immune reaction.
Russian scientists offer a more effective method of fighting glioma. The authors of the development were researchers from the Institute of Chemical Biology and Fundamental Medicine of the Siberian Branch of the Russian Academy of Sciences.
Glioma is a hard-to-treat brain cancer. Novosibirsk scientists propose to use chemotherapy and oncolytic viruses to fight the disease.
Instead of standard treatment with tumor removal and chemotherapy, scientists propose to “infect” cancer cells with oncolytic virus, created on the basis of the smallpox vaccine virus used in the USSR until the 1980s.
In the State Research Center of Virology and Biotechnology “Vector” finalized the virus, removing genes responsible for reproduction in healthy tissues. Instead of them, the virus was embedded with genes that activate the immune system.
As a result, the virus destroys cancer cells from the inside, making them “visible” to the immune system.
At the same time, the virus reproduces only in the cancer cell and does not pose a threat to human health.
The method has already been tested on animals and has shown effectiveness.
Earlier it was reported about the creation of a unique vaccine against several types of cancer. Also in Novosibirsk, scientists were able to make progress in the treatment of viral diseases.